A cooperative project between the MIT and the IZI received the support of "Seed Fund", a joint funding initiative of the Massachusetts Institute of Technology and the University of Stuttgart.
In this interdisciplinary project, the Olayioye Group will team up with the Guo Lab to study how the interplay between biomechanical cues and spatial positioning affects cancer cell fate in 3D. By combing CRISPR/Cas9 epigenetic editing (Lungu), cancer cell biology (Olayioye) and biophysical (Guo) methodologies, this work is anticipated to contribute key insights into the molecular mechanisms of early metastatic dissemination.