22. Juni 2018

Contribution to a study published in Plant Cell by Ismael Sánchez-González and Monilola Olayioye on the fate of m6A RNA degradation products

m6A RNA Degradation Products are Catabolized by an Evolutionarily Conserved N6-methyl-AMP Deaminase in Plant and Mammalian Cells.

Mingjia Chen, Mounashree J. Urs, Ismael Sánchez-González, Monilola A. Olayioye, Marco Herde, Claus-Peter Witte.
 
 
The study identifies a multilayer molecular protection system functioning in Arabidopsis and human cells that suppresses the formation of N6-methyl-ATP, possibly to prevent random insertion of N6-methylated adenine into RNA.
http://www.plantcell.org/content/early/2018/06/08/tpc.18.00236
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